Many buyers treat every 5.7 Hemi lifter as interchangeable, then discover that a mismatch can turn a routine repair into a costly delay.
The Best Aftermarket Lifters for 5.7 Hemi merit a closer comparison because listings span different model years, operating systems, and replacement numbers. This roundup puts those claims side by side, helping you spot meaningful differences before you read the product details.
Key Takeaways
- Confirm MDS or non-MDS configuration first, because the two lifter arrangements are not interchangeable.
- Match the exact vehicle year, engine size, and replacement part number against the listing rather than relying on a broad fitment claim.
- Check the piece count and verify whether the package includes plugs or gaskets, especially if the listing describes a kit.
- Treat compatibility claims spanning 5.7L, 6.1L, 6.2L, and 6.4L engines as a prompt to verify your exact application.
- Favor listings that show clear OEM cross-reference numbers and a defined return policy, since catalog errors can be expensive after installation.
| Top MDS Match |  |
Koomaha MDS Hemi Lifter Set, 5.7L | MDS Replacement Focus | Two Listed Part Numbers | Broad Brand Coverage | View on Amazon | Read Review |
| Plug-Ready Non-MDS | Non-MDS Hemi Lifters, 5.7L | Non-MDS Lifter Design | Plugs Included | Three Hemi Sizes | View on Amazon | Read Review | |
| Broad Year Coverage |  |
MDS Hemi Lifters, 5.7L V8 | MDS Replacement Focus | Two Listed Numbers | Long Model-Year Range | View on Amazon | Read Review |
| 16-Piece MDS Set |  |
MDS Hemi Lifters, 16-Piece Set | Full 16-Piece Set | MDS Lifter Design | Broad Vehicle Coverage | View on Amazon | Read Review |
| Jeep-Focused MDS Pick |  |
MDS Hemi Lifters, Jeep Fit | MDS Replacement Lifters | Jeep Application Coverage | Two Listed Numbers | View on Amazon | Read Review |
| Full Repair Bundle |  |
MDS Hemi Repair Kit, Camshaft | Lifters, Camshaft, Gaskets | Repair-Oriented Bundle | Four Listed References | View on Amazon | Read Review |
| Multi-Engine Non-MDS |  |
Non-MDS Hemi Lifters, Multi-Size | Non-MDS Configuration | Four Hemi Sizes | Two Listed Numbers | View on Amazon | Read Review |
| Plug-Included Alternative |  |
Non-MDS Hemi Lifters, Plugs | Plugs Included | Earlier Model Coverage | Three Hemi Sizes | View on Amazon | Read Review |
| Part-Number Specialist |  |
5038785AD MDS Hemi Lifters | Clear 5038785AD Reference | Broad Model List | MDS Lifter Design | View on Amazon | Read Review |
| Late-Model MDS Choice |  |
GELUOXI MDS Hemi Lifters, 5.7L | Late-Model Coverage | Two Listed Numbers | MDS-Specific Listing | View on Amazon | Read Review |
More Details on Our Top Picks
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Koomaha MDS Hemi Lifter Set, 5.7L
Start with this set if your 5.7L Hemi uses MDS and you need a direct lifter replacement. The Koomaha listing covers Chrysler, Jeep, and Dodge applications, giving you a practical option for a focused repair.
Its key strengths are MDS-specific fit, two cross-reference numbers, and broad brand coverage. You still need to confirm your year, engine configuration, and MDS setup, since the listing does not provide a detailed compatibility chart or package count.
- Brand:Koomaha
- Lifter Type:MDS
- Engine Size:5.7L Hemi
- Vehicle Fit:Chrysler, Jeep, Dodge
- Part Number:53021726AD / 53021726AE
- Additional Feature:MDS lifter set
- Additional Feature:Chrysler, Jeep, Dodge applications
- Additional Feature:53021726AD and AE references
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Non-MDS Hemi Lifters, 5.7L
Choose this set for a non-MDS repair where the included plugs are useful. It covers several Hemi displacements and a 2003-2014 span across Dodge, Jeep, and Chrysler applications.
The strongest points are plug inclusion, non-MDS design, and two listed part numbers. The limitation is fitment complexity, because the broad 5.7L, 6.1L, and 6.4L range requires an exact engine and model check before ordering.
- Lifter Type:Non-MDS
- Engine Size:5.7L, 6.1L, 6.4L HEMI
- Vehicle Fit:2003-2014 Dodge, Jeep, Chrysler
- Part Number:5038784AD / 53021720AB
- Additional Feature:Non-MDS lifters
- Additional Feature:Plugs included
- Additional Feature:5.7L, 6.1L, 6.4L coverage
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MDS Hemi Lifters, 5.7L V8
For a later-model 5.7L Hemi, this listing offers a straightforward MDS lifter replacement route. Its stated 2005-2021 coverage spans Dodge, Jeep, and Chrysler vehicles, which suits a vehicle-specific parts search.
You get two replacement numbers, broad year coverage, and a focused 5.7L V8 application. The tradeoff is a lean listing with no stated piece count or added installation parts, so it is not presented as a complete valvetrain kit.
- Lifter Type:MDS
- Engine Size:5.7L V8
- Vehicle Fit:2005-2021 Dodge, Jeep, Chrysler
- Part Number:53021726AE / 53021726AD
- Additional Feature:2005-2021 application range
- Additional Feature:MDS design
- Additional Feature:Two listed replacement numbers
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MDS Hemi Lifters, 16-Piece Set
The 16-piece format makes this a sensible pick when you want a full lifter set for a 5.7L MDS engine. Its stated 2005-2021 coverage includes Dodge, Jeep, and Chrysler applications.
That clear 16-piece count, MDS design, and two listed part numbers simplify initial comparison. You still need to confirm the exact application and whether your repair requires other valvetrain components, since the listing does not identify a camshaft, gasket set, or hardware.
- Lifter Type:MDS
- Engine Size:5.7L V8
- Vehicle Fit:2005-2021 Dodge, Jeep, Chrysler
- Part Number:53021726AD / 53021726AE
- Package Count:16 pieces
- Additional Feature:16-piece package
- Additional Feature:MDS lifter design
- Additional Feature:5.7L V8 application
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MDS Hemi Lifters, Jeep Fit
Jeep owners can shortlist this option if their 5.7L application falls within the listed 2005-2021 range. It also names Dodge and Chrysler coverage, so the part is not limited to one badge.
Expect a focused MDS replacement, broad model-family targeting, and a listed 53021726AE/AD part-number pair. The title gives no package count or supporting parts, which makes it better suited to a lifter-only repair than a complete top-end rebuild.
- Lifter Type:MDS
- Engine Size:5.7L
- Vehicle Fit:2005-2021 Jeep, Dodge, Chrysler
- Part Number:53021726AE / 53021726AD
- Additional Feature:MDS replacement lifters
- Additional Feature:Jeep, Dodge, Chrysler coverage
- Additional Feature:53021726AE and AD references
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MDS Hemi Repair Kit, Camshaft
If your repair has grown beyond lifters, this is the most comprehensive package in the group. The listing combines MDS lifters, a camshaft, and a head gasket set for 2009-2018 Dodge Ram 1500, Durango, and Chrysler Aspen applications.
That bundled repair format can reduce the number of separate components you need to source, with four listed part references to check against your build. Its limitation is scope, since the title names selected vehicles and years but does not provide detailed camshaft or gasket compatibility information.
- Lifter Type:MDS
- Engine Size:5.7L Hemi
- Vehicle Fit:2009-2018 Dodge, Chrysler
- Part Number:HS26423PT / 53022263AF / 53021726AD / 53021726AE
- Additional Feature:MDS lifters included
- Additional Feature:Camshaft included
- Additional Feature:Head gasket set included
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Non-MDS Hemi Lifters, Multi-Size
Pick this one for a non-MDS Hemi that falls within its wider engine range. It lists 5.7L, 6.1L, 6.2L, and 6.4L applications across Chrysler, Jeep, and Dodge vehicles from 2006-2018.
Multiple engine sizes and two replacement numbers give you useful cross-check points. The wide compatibility claim is also the caution, since a non-MDS part must match your engine’s valvetrain configuration, year, and application exactly.
- Lifter Type:Non-MDS
- Engine Size:5.7L, 6.1L, 6.2L, 6.4L
- Vehicle Fit:2006-2018 Chrysler, Jeep, Dodge
- Part Number:53021720AD / 53021720AE
- Additional Feature:Non-MDS design
- Additional Feature:5.7L through 6.4L coverage
- Additional Feature:53021720AD and AE references
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Non-MDS Hemi Lifters, Plugs
Use this listing if you need non-MDS lifters plus plugs for an earlier Hemi application. Its 2003-2014 coverage and support for 5.7L, 6.1L, and 6.4L engines make it a flexible candidate for older Dodge, Jeep, and Chrysler vehicles.
Plug inclusion is the practical advantage, alongside the single listed part number and broad displacement coverage. The limitation is that the title does not state a piece count or spell out the exact plug quantity, so check the package contents before purchase.
- Lifter Type:Non-MDS
- Engine Size:5.7L, 6.1L, 6.4L HEMI
- Vehicle Fit:2003-2014 Dodge, Jeep, Chrysler
- Part Number:5038784AD
- Additional Feature:Non-MDS lifters
- Additional Feature:Plugs included
- Additional Feature:2003-2014 application range
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5038785AD MDS Hemi Lifters
Consider this part when your search starts with 5038785AD rather than a vehicle name. The listing reaches across 2005-2018 Dodge, Jeep, and Chrysler vehicles, including Ram 1500, Challenger, Charger, Durango, Magnum, 300, Aspen, Commander, and Grand Cherokee.
That MDS valve-lifter design and extensive model list make it useful for cross-referencing a broad parts search. Its drawback is the same breadth, because the title does not provide a package count or separate fitment details for each vehicle, so verify your exact application.
- Lifter Type:MDS
- Engine Size:5.7L V8
- Vehicle Fit:2005-2018 Dodge, Jeep, Chrysler
- Part Number:5038785AD
- Additional Feature:5038785AD reference
- Additional Feature:MDS valve lifters
- Additional Feature:Dodge, Jeep, Chrysler applications
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GELUOXI MDS Hemi Lifters, 5.7L
Late-model owners looking for a 5.7L MDS replacement can use this GELUOXI listing as a direct comparison candidate. It covers 2006-2021 Jeep, Dodge, and Chrysler applications and names both 53021726AD and 53021726AE.
Two cross-reference numbers, broad year coverage, and a clear MDS designation are the useful points here. The title does not state a package count or include a camshaft, gasket set, or other repair hardware, so it is aimed at a lifter-only replacement.
- Brand:GELUOXI
- Lifter Type:MDS
- Engine Size:5.7L V8
- Vehicle Fit:2006-2021 Jeep, Dodge, Chrysler
- Part Number:53021726AD / 53021726AE
- Additional Feature:MDS lifter replacement
- Additional Feature:2006-2021 coverage
- Additional Feature:53021726AD and AE references
Frequently Asked Questions
Will any aftermarket lifter fit every 5.7 Hemi?
No. Model year, engine revision, and MDS status affect fitment, even when two engines share the 5.7-liter displacement. Check the seller's application chart against your VIN and compare the listed OEM reference number. Also confirm the lifter's body dimensions, guide-tray design, and compatibility with your camshaft. Do not rely on a listing that only says “5.7 Hemi.”
How do MDS and non-MDS lifters differ?
An MDS 5.7 Hemi typically uses eight MDS lifters and eight standard lifters. The MDS units can collapse under electronic control to deactivate four cylinders, while standard lifters remain fixed. If you are retaining MDS, use the correct lifter locations and matching hardware. For an MDS delete, use non-MDS lifters as part of a properly planned conversion rather than mixing lifter types.
Can I replace the lifters without replacing the camshaft?
Sometimes, but inspect the cam carefully first. If the lobes are smooth and within specification, a lifter-only repair may be appropriate, although many rebuilders install a complete lifter set after a failure. Never place a new lifter against a worn cam lobe, scored surface, or damaged roller track. That combination can create another failure quickly, turning a parts replacement into a full valvetrain repair.
What symptoms point to a failing 5.7 Hemi lifter?
Common warning signs include a persistent ticking noise, a cylinder misfire, rough idle, reduced valve lift, or metal in the oil. Noise that follows engine speed can point to a lifter or cam problem, but an exhaust-manifold leak can create a similar Hemi tick. Use scan data, an oil-pressure check, and a valvetrain inspection to confirm the cause. Do not replace lifters based on sound alone, especially if the engine also has a damaged rocker, pushrod, cam lobe, or low oil pressure.
What else should I replace or inspect during a lifter job?
Plan on checking or replacing the lifter trays, gaskets, and oil and filter. Inspect the cam lobes, pushrods, rocker arms, lifter bores, and MDS components for wear or debris before closing the engine. Follow the manufacturer's priming instructions, verify valve preload, and confirm oil pressure before sustained engine speed. Addressing damaged supporting parts now is far less costly than removing the top end again.
